FAUC 1036( FAUC1036 | FAUC-1036 )

Catalog No. M12893 CAS No. 1869983-83-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

FAUC 1036
Note

Research use only, not for human use.
Brief Description

A potent, biased allosteric agonist of CXCR3 (pEC50=6.64).
Description

A potent, biased allosteric agonist of CXCR3 (pEC50=6.64), selectively induces chemotaxis and receptor internalization, and induces β-arrestin 2 recruitment without any stimulation of G proteins.
In Vitro

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In Vivo

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Synonyms

FAUC1036 | FAUC-1036
Pathway

GPCR/G Protein
Target

Chemokine Receptor
Recptor

Chemokine Receptor
Research Area

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Indication

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CAS Number

1869983-83-4
Formula Weight

744.933
Molecular Formula

C45H52N4O6
Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

tert-Butyl {(S)-1-[(2,2-diphenylethyl)amino]-1-oxo-6-[(S)-2-(4-oxo-4-phenylbutanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido]hexan-2-yl}carbamate

1. Milanos L, et al. J Med Chem. 2016 Mar 10;59(5):2222-43. 2. Milanos L, et al. Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15277-15281.

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